How is the right dose of GLP-1 agonists given?
In this video, Dr Ravi Assomull describes how dosing for GLP-1 agonists like Mounjaro is carefully tailored. He explains why it’s essential to start at a low dose to minimise side effects and how doses are adjusted based on weight loss progress. The goal is to find the lowest effective dose while maintaining benefits.
Have a question about your own heart health? Book a consultation with Dr Assomull – no GP referral needed, appointments typically within one working day.
Transcript
To get you on the right dose of GLP-1 agonist, it's critical we start you on the lowest dose to make sure that your body, and specifically your gastrointestinal tract, get used to it. So typically for a drug like Mounjaro, which is our preferred GLP-1 agonist, we start you at a dose of 2.5mg, which we ask you to take for a month. After that, we tend to titrate that up to 5mg.
We then keep tracking things, and if you continue to lose weight at that dose, we stop. If we find that you've hit a plateau with your weight loss, we may increase the Mounjaro all the way up to the maximum dose of 15mg. It's fair to say that actually most people need significantly less than the maximum dose of 15mg.
More on glp-1(weight loss) injections
0:25
What is a GLP-1 agonist?
0:20
How can I qualify for GLP-1 medication?
0:14
Can GLP-1 agonists be used in combination with other medications?
0:30
Who shouldn’t take GLP-1 medication?
0:20
What heart concerns might improve with the use of GLP-1 agonists?
0:23
How will I know if GLP-1 medication is helping my heart?